Work

LGA: a method for finding 3D similarities in protein structures

Year: 2003

Type: article

Abstract: We present the LGA (Local-Global Alignment) method, designed to facilitate the comparison of protein structures or fragments of protein structures in sequence dependent and sequence independent modes. The LGA structure alignment program is available as an online service at http://PredictionCenter.llnl.gov/local/lga. Data generated by LGA can be successfully used in a scoring function to rank the level of similarity between two structures and to allow structure classification when many proteins are being analyzed. LGA also allows the clustering of similar fragments of protein structures.

Source: Nucleic Acids Research

DOI: 10.1093/nar/gkg571

Author: A. Zemla

Institution: Lawrence Livermore National Laboratory

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: U.S. Department of Energy, Lawrence Livermore National Laboratory

Awards: G1101028137, G1702950523, G3177268909, G6445123630