Work

Vaccination with Purified Dr Fimbriae Reduces Mortality Associated with Chronic Urinary Tract Infection Due toEscherichia coliBearing Dr Adhesin

Year: 2004

Type: article

Abstract: The vaccination of C3H/HeJ mice with Escherichia coli Dr fimbrial antigen reduced mortality associated with an experimental urinary tract infection due to a homologous strain bearing Dr adhesin. Immune sera with high titers of anti-Dr antibody inhibited bacterial binding to bladders and kidneys but did not affect the rate of renal colonization.

Source: Infection and Immunity

DOI: 10.1128/iai.73.1.627-631.2005

Authors: Pawel Goluszko, Elzbieta Goluszko, Bogdan Nowicki, Stella Nowicki, Vsevolod Popov, Hui-Qun Wang

Institution: The University of Texas Medical Branch at Galveston

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Diabetes and Digestive and Kidney Diseases