Work

The endocrine and local control of ovarian follicle development in the ewe

Year: 2009
Type: article
Abstract: Follicle development can be divided into gonadotrophin-independent, gonadotrophin-responsive and gonadotrophin-dependent phases. The basic level of control of folliculogenesis lies with the actions of an extensively observed but poorly understood range of somatic and germ cell derived local factors that constitute an intrafollicular developmental cascade that regulates the proliferative and differentiative phases of follicle development. As follicle development progresses, the follicle become increasingly responsive to the actions of the pituitary gonadotrophins FSH and LH and during these phases of development local factors act to modulate the actions of gonadotrophins so that the fate of each follicle depends on an intra-
Language: English
Open Access status: gold
OpenAlex ID: W2111279236
FWCI: 2.728
Cites: 79
Cited by: 20
Related to: 10