An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles
Year: 2013
Type: review
Abstract: This review which is the second in this series summarises the most common synthetic routes as applied to the preparation of many modern pharmaceutical compounds categorised as containing a six-membered heterocyclic ring. The reported examples are based on the top retailing drug molecules combining synthetic information from both scientific journals and the wider patent literature. It is hoped that this compilation, in combination with the previously published review on five-membered rings, will form a comprehensive foundation and reference source for individuals interested in medicinal, synthetic and preparative chemistry.
DOI: 10.3762/bjoc.9.265
Authors: Marcus Baumann, Ian R Baxendale
Institution: Durham University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
Funder: Royal Society
OpenAlex ID: W2111537995