Work

Microarrays in primary breast cancer--lessons from chemotherapy studies.

Year: 2001

Type: article

Abstract: Current development in molecular techniques has extended the opportunities to explore genetic alterations in malignant tissue. There is a need to improve prognostication and, in particular, to understand the mechanisms of treatment resistance in different tumours. Gene analyses by microarrays allow concomitant analyses of several genes in concert, providing new opportunities for tumour classification and understanding of key biological disturbances. This paper outlines our continuing studies exploring prognostic and, we hope, predictive factors in breast cancer therapy.

Source: Endocrine Related Cancer

DOI: 10.1677/erc.0.0080259

Authors: P E L√∏nning, T S√∏rlie, C M Perou, P O Brown, D Botstein, A L B√∏rresen-Dale

Institutions: Haukeland University Hospital, University of Bergen

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Kreftforeningen, National Cancer Institute