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Peripherally Cross-Linking the Shell of Core-Shell Polymer Micelles Decreases Premature Release of Physically Loaded Combretastatin A4 in Whole Blood and Increases its Mean Residence Time and Subsequent Potency Against Primary Murine Breast Tumors After IV Administration

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Year: 2014
Type: article
Source: Pharmaceutical Research
DOI: 10.1007/s11095-014-1515-z
Authors: Rajesh R. Wakaskar, Sai Praneeth R. Bathena, Shailendra B. Tallapaka, Vishakha V. Ambardekar, Nagsen Gautam, Rhishikesh Thakare, Samantha M. Simet, Stephen M. Curran, Rakesh K. Singh, Yuxiang Dong, Joseph A. Vetro
Institutions: Nebraska Medical Center, University of Nebraska Medical Center, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. (United States)
Language: English

Topic: Nanoparticle-Based Drug Delivery
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources
Awards: Pancreatic Tumor Micro-environment Network, Nebraska Center for Nanomedicine, Bioscope II - AFM system for Nanoimaging Core Facility, Nebraska Center for Nanomedicine, Development of Targeted Nanogels for siRNA Delivery to Tumor Vasculature
OpenAlex ID: W2111795539
FWCI: 1.639
Cites: 49
Cited by: 32
Related to: 10
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