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Mitochondrial Bax Translocation Accelerates DNA Fragmentation and Cell Necrosis in a Murine Model of Acetaminophen Hepatotoxicity

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Year: 2007
Type: article
Source: Journal of Pharmacology and Experimental Therapeutics
DOI: 10.1124/jpet.107.129445
Authors: Mary Lynn Bajt, Anwar Farhood, John J. Lemasters, Hartmut Jaeschke
Institution: University of Kansas Medical Center
Language: English

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: G2108293184, G2704092023, Mechanisms of Neutrophil-induced Liver Toxicity, Mitochondrial Dysfunction and Drug Hepatotoxicity
OpenAlex ID: W2111834129
FWCI: 5.728
Cites: 42
Cited by: 188
Related to: 10
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