Work

Intellectual abilities among survivors of childhood leukaemia as a function of CNS irradiation.

Year: 1978

Type: article

Abstract: Twenty-eight children in remission at least 2 years after completing chemotherapy for acute lymphoblastic leukaemia were assessed on standardised psychological tests. It was found that 7 who never had central nervous system (CNS) irradiation and 9 having prophylactic CNS irradiation at least 6 months after diagnosis tended to perform at average or above levels, while those 10 each having prophylactic CNS irradiation (within 2 months of diagnosis) were generally of lower ability. Within the latter group, 3 children showed serious intellectual impairments, while the group as a whole functioned especially poorly on quantitative tasks and those involving speeded performance with abstract material. General language ability was not affected. Practical and theoretical implantation are discussed.

Source: Archives of Disease in Childhood

DOI: 10.1136/adc.53.5.391

Author: C Eiser

Institution: Great Ormond Street Hospital

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Hospital for Sick Children