Work

Estimating optical properties in layered tissues by use of the Born approximation of the radiative transport equation

Year: 2006

Type: article

Abstract: We use the Born approximation of the radiative transport equation to recover simultaneously the absorption and scattering coefficients in a single layer of a two-layer tissue sample from reflectance data. This method reduces the estimation of both optical properties to a single linear, least-squares problem. It is valid over length scales smaller than a transport mean free path and hence is useful for epithelial tissue layers. We demonstrate the accuracy of this method by using spatially resolved reflectance data computed with Monte Carlo simulations.

Source: Optics Letters

DOI: 10.1364/ol.31.001088

Authors: Arnold D. Kim, Carole Hayakawa, Vasan Venugopalan

Institutions: University of California, Merced, University of California System, University of California, Irvine

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources

Awards: Photon Migration for Measurement of Small Tissue Volumes, A Laser Microbeam Biotechnology Resource, Mathematical investigation of light propagation in tissues for physiological monitoring and tissue imaging, G9000199918