Work

Habituation in neural processing and subjective perception of respiratory sensations

Year: 2010

Type: article

Abstract: Reduced perception of respiratory sensations is associated with negative treatment outcome in asthma. We examined whether habituation in the neural processing of repeatedly experienced respiratory sensations may underlie subjective reports of reduced respiratory perception. Respiratory-related evoked potentials (RREP) elicited by inspiratory occlusions and reports of respiratory perception were compared between early and late experimental periods in healthy subjects. Reports of respiratory perception were reduced during late, compared to early, experimental periods. This was paralleled by reduced magnitudes in RREP components N1, P2, and P3 in late, compared to early, experimental periods. Habituation in the neural processing of respiratory sensations is a potential mechanism that underlies subjective reports of reduced respiratory perception and might represent a risk factor for reduced perception of respiratory sensations in asthma.

Source: Psychophysiology

DOI: 10.1111/j.1469-8986.2010.01141.x

Authors: Andreas Von Leupoldt, Andrea Vovk, Margaret M. Bradley, Peter J. Lang, Paul W. Davenport

Institutions: Universität Hamburg, University of Florida, University Medical Center Hamburg-Eppendorf

Language: English

Topic: Neuroscience of respiration and sleep

Subfield: Endocrine and Autonomic Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Mental Health