Work

Highly enantioselective aldol reaction: development of a new chiral auxiliary from cis-1-amino-2-hydroxyindan

Year: 1992

Type: article

Abstract: Boron enolates obtained from optically active oxazolidinone derivative of cis-1-amino-2-hydroxyindan are reacted with various aldehydes to provide highly enantioselective aldol products in good yields.

Source: Journal of the Chemical Society Chemical Communications

DOI: 10.1039/c39920001673

Authors: Arun K. Ghosh, Tien T. Duong, Sean P. McKee

Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funder: National Institute of General Medical Sciences

Award: DESIGN AND SYNTHESIS OF NONPEPTIDE PROTEASE INHIBITORS

OpenAlex ID: W2112682810

FWCI: 2.298

Cites: 14

Cited by: 54

Related to: 10