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Onset timing of cross‐sensory activations and multisensory interactions in auditory and visual sensory cortices

Year: 2010
Type: article
Abstract: Here we report early cross-sensory activations and audiovisual interactions at the visual and auditory cortices using magnetoencephalography (MEG) to obtain accurate timing information. Data from an identical fMRI experiment were employed to support MEG source localization results. Simple auditory and visual stimuli (300-ms noise bursts and checkerboards) were presented to seven healthy humans. MEG source analysis suggested generators in the auditory and visual sensory cortices for both within-modality and cross-sensory activations. fMRI cross-sensory activations were strong in the visual but almost absent in the auditory cortex; this discrepancy with MEG possibly reflects the influence of acoustical scanner noise in fMRI. In the primary auditory cortices (Heschl's gyrus) the onset of activity to auditory stimuli was observed at 23 ms in both hemispheres, and to visual stimuli at 82 ms in the left and at 75 ms in the right hemisphere. In the primary visual cortex (Calcarine fissure) the activations to visual stimuli started at 43 ms and to auditory stimuli at 53 ms. Cross-sensory activations thus started later than sensory-specific activations, by 55 ms in the auditory cortex and by 10 ms in the visual cortex, suggesting that the origins of the cross-sensory activations may be in the primary sensory cortices of the opposite modality, with conduction delays (from one sensory cortex to another) of 30-35 ms. Audiovisual interactions started at 85 ms in the left auditory, 80 ms in the right auditory and 74 ms in the visual cortex, i.e., 3-21 ms after inputs from the two modalities converged.
DOI: 10.1111/j.1460-9568.2010.07213.x
Authors: Tommi Raij, Jyrki Ahveninen, Fa‐Hsuan Lin, Thomas Witzel, Iiro P. Jääskeläinen, Benjamin Letham, Emily Israeli, Cherif Sahyoun, Christos Vasios, Steven Stufflebeam, Matti Hämäläinen, John W. Belliveau
Institutions: Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts Institute of Technology, National Taiwan University, Harvard–MIT Division of Health Sciences and Technology, Aalto University
Language: English
Field: Psychology
Open Access status: green
Funders: Harvard Catalyst, National Institute for Health and Care Research, National Health Research Institutes, National Institutes of Health, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1815946096, Superior Temporal Gyrus function in Schizophrenia, Harvard Clinical and Translational Science Center (UL1), Spatiotemporal Brain Imaging of Human Auditory Cognition, Dynamic Magnetic Resonance Inverse Imaging of the Human Brain, Center for Functional Imaging Technologies, Dynamic imaging of oscillatory brain networks controlling selective attention, Spatiotemporal Imaging of Human Visual System Processing, Neural mechanisms: Learned audio-visuo-motor integration, Neuroimaging Training Program
OpenAlex ID: W2113099597
FWCI: 15.42
Cites: 81
Cited by: 133
Related to: 10