Work

REBASE: restriction enzymes and methyltransferases

Year: 2003

Type: article

Abstract: REBASE contains comprehensive information about restriction enzymes, DNA methyltransferases and related proteins such as nicking enzymes, specificity subunits and control proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data. Homing endonucleases are also included. REBASE contains the most complete and up-to-date information about the methylation sensitivity of restriction endonucleases. In addition, there is extensive information about the known and putative restriction-modification (R-M) systems in more than 100 sequenced bacterial and archaeal genomes. The data is available on the web (http://rebase.neb.com/rebase/rebase.html), through ftp (ftp.neb.com) and as monthly updates via email.

Source: Nucleic Acids Research

DOI: 10.1093/nar/gkg069

Authors: R. J. Roberts, Tamas Vincze, Janos Posfai, Dana Macelis

Institution: New England Biolabs (United States)

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: U.S. Department of Energy, U.S. National Library of Medicine

Awards: REBASE-The Restriction Enzyme Database, FUNCTIONAL MOTIFS IN BIOLOGICAL SEQUENCES