Consumo e bioproteção de componentes do café à presença de micotoxinas em ratos Wistar
Year: 2011
Type: dissertation
Abstract: Coffee is nothing less than the second most consumed beverage in the world; its taste and attractive aroma justify its acceptance. Several studies have been conducted to determine their effects on human health. Confronted with evidence found in literature, this study sought to confront, by "in vivo" testing, the bioprotective action of two the most important chemical compounds in coffee (chlorogenic acids and cafestol) and two known mycotoxins (ochratoxin A and aflatoxin B1). The experiment was composed of four biological tests. The young Winster male rats were used, kept in a controlled environment with 12 hours photoperiod and ambient temperature of about 25 oC, all in individual metabolic cages with access to controlled food (15g/day) and "ad libtum" water. During the each test last four weeks, each animal received 50ng of toxin/day on 3g of powdered milk, added by 1.5 ml of distilled water and shaped into a sphere. Animals from the negative toxin groups received the same treatment without the addition of mycotoxin. It was possible to see bioprotective action forward to mycotoxins, especially by chlorogenic acids, improving the weight gain and the synthesis of muscle and liver glycogen. It is suggest testing for a longer period of time to confirm all the found evidences, especially because was not find difference on biochemical and histopathological exams. The percentage data were compared by Scott Knott and T of Student tests at 5% of probability.
Author: Juliano Silva Rocha
Language: Portuguese
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2113814837