Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation
Year: 2015
Type: article
Abstract: The role of hematopoietic cell transplantation (HCT) in the therapy of Hodgkin lymphoma (HL) in pediatric and adult patients is reviewed and critically evaluated in this systematic evidence-based review. Specific criteria were used for searching the published literature and for grading the quality and strength of the evidence and the strength of the treatment recommendations. Treatment recommendations based on the evidence are included and were reached unanimously by a panel of HL experts. Both autologous and allogeneic HCT offer a survival benefit in selected patients with advanced or relapsed HL and are currently part of standard clinical care. Relapse remains a significant cause of failure after both transplant approaches, and strategies to decrease the risk of relapse remain an important area of investigation.
Institutions: Memorial Sloan Kettering Cancer Center, Cornell University, Weill Cornell Medicine, Donostiako Unibertsitate Ospitalea, Dana-Farber Cancer Institute, University of Minnesota, City Of Hope National Medical Center, City of Hope, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Tufts Medical Center, Stanford Medicine, Stanford University, The University of Texas MD Anderson Cancer Center, Vanderbilt University Medical Center, University of North Carolina at Chapel Hill, Nebraska Medical Center, Fred Hutch Cancer Center
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2114043234