Association Between Oxidative Stress Markers and Metabolic Disturbances in Overweight and Obese Women
Year: 2009
Type: article
Study design: Observational Study
Abstract: The aim of study was to investigate the association between oxidative stress and anthropometric and metabolic parameters in middle-aged, overweight or obese women.Venous blood samples were taken from each subject after an overnight fast, and the following parameters were assessed: plasma total antioxidant status (TAS), plasma concentrations of thiobarbituric acid reactive substances (TBARS), serum levels of antibodies against oxidized low density lipoproteins (oLAB), serum lipid profiles, and serum glucose and insulin concentrations.Additionally, serum low density lipoprotein (LDL) cholesterol and insulin resistance indices and atherogenic index of plasma (AIP) were calculated.Correlations were noted between plasma thiobarbituric reactive substances (TBARS), antibodies to oxidized LDL (oLAB), and total antioxidant status (TAS); and blood pressure (BP), insulin resistance parameters and lipids profile.The levels of antibodies to oxidatively modified low-density lipoproteins oLAB correlated with systolic and diastolic BP, TAS correlated negatively with the atherogenic index of plasma (AIP).An association was found between oxidative stress and BP, and lipid risk factors in obese and overweight women.
Source: Wielkopolska Digital Library
Language: English
Subfield: Biochemistry (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2114851553