Work

Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma

Year: 2013

Type: article

Abstract: The combination of BRAF-targeted agents with immune checkpoint inhibitors represents a recent advance in the treatment of melanoma, even though each of these therapeutic approaches alone has specific limitations. Increasing evidence suggests indeed the existence of a synergistic interaction between these therapeutic modalities.

Source: OncoImmunology

DOI: 10.4161/onci.24320

Authors: Zachary A. Cooper, Dennie T. Frederick, Zain Ahmed, Jennifer A. Wargo

Institution: Massachusetts General Hospital

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,913