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A systematic review of dental late effects in survivors of childhood cancer

Year: 2013
Type: review
Study design: Systematic Review
Abstract: Survivors of childhood cancer are at risk for dental late effects. This systematic review summarizes associations between treatment exposures and dental late effects among survivors of childhood cancer. We included investigations with at least 20 study participants conducted for 2 or more years after completion of childhood, adolescent, or young adult cancer therapy. This review suggests both independent and additive effects of radiotherapy and chemotherapy on dental complications, and identifies vulnerable groups with specific host and treatment characteristics. This summary provides information that will assist clinicians to prevent, detect, and facilitate early intervention for dental late effects.
DOI: 10.1002/pbc.24842
Authors: Prasad L. Gawade, Melissa M. Hudson, Sue C. Kaste, Joseph P. Neglia, Louis S. Constine, Leslie L. Robison, Kirsten K. Ness
Institutions: St. Jude Children's Research Hospital, University of Tennessee Health Science Center, University of Minnesota, University of Minnesota Medical Center, University of Rochester Medicine, University of Rochester
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W2115100758
FWCI: 1.019
Cites: 89
Cited by: 156
Related to: 10