Year: 1996
Type: article
Abstract: Twelve mycobacterial antigens were compared for induction of gamma interferon (IFN-gamma) secretion by human blood mononuclear cells of patients with leprosy. Fractionated Mycobacterium leprae antigens containing cell wall proteins or cytosolic and membrane proteins induced good IFN-gamma responses in tuberculoid leprosy patients. Lipoarabinomannan from M. tuberculosis Erdman and M. leprae mycolylarabinogalactan peptidoglycan were the poorest IFN-gamma inducers.
Source: Infection and Immunity
Authors: H M Dockrell, S K Young, K Britton, P J Brennan, B Rivoire, M F Waters, S B Lucas, F Shahid, M Dojki, T J Chiang, Q Ehsan, K P McAdam, R Hussain
Institution: London School of Hygiene & Tropical Medicine
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2115372281