Work

Antipsychotics in the treatment of autism

Year: 2008

Type: article

Abstract: Atypical antipsychotics have become indispensable in the treatment of a variety of symptoms in autism. They are frequently used to treat irritability and associated behaviors including aggression and self injury. They may also be efficacious for hyperactivity and stereotyped behavior. This review presents the rationale for the use of this drug class in autism and reviews the most important studies published on this topic to date. Significant adverse effects, including weight gain and the possibility of tardive dyskinesia, are reviewed. Future research directions are discussed.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci32483

Authors: David J. Posey, Kimberly A. Stigler, Craig A. Erickson, Christopher J. McDougle

Institutions: Christian Sarkine Autism Treatment Center, Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis

Language: English

Topic: Autism Spectrum Disorder Research

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Housing and Urban Development, National Alliance for Research on Schizophrenia and Depression, School of Medicine, Indiana University, National Institute of Mental Health