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Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study

Year: 2008
Type: article
Abstract: OBJECTIVE: The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components. RESEARCH DESIGN AND METHODS: A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome. RESULTS: At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40-0.95]) and in the prevalence of abdominal obesity (0.48 [0.28-0.81]). CONCLUSIONS: The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.
DOI: 10.2337/dc07-1117
Authors: Pirjo Ilanne-Parikka, Johan G. Eriksson, Jaana Lindström, Markku Peltonen, Sirkka Aunola, Helena Hämäläinen, Sirkka Keinänen-Kiukaanniemi, Mauri Laakso, Timo T. Valle, Jorma Lahtela, Matti Uusitupa, Jaakko Tuomilehto, on behalf of the Finnish Diabetes Prevention Study Group
Institutions: Finnish Diabetes Association, Pirkanmaa Hospital District, University of Helsinki, Finnish Institute for Health and Welfare, Social Insurance Institution, Oulu Deaconess Institute, University of Oulu, Oulu University Hospital, Tampere University Hospital, University of Eastern Finland
Language: English
Field: Medicine
Open Access status: bronze
Funders: Helsingin Yliopisto, Juho Vainion Säätiö, Kuopion Yliopistollinen Sairaala, Novo Nordisk, Oulun Yliopisto, Novo Nordisk Fonden, Pirkanmaan Sairaanhoitopiiri, Tays, Diabetestutkimussäätiö
OpenAlex ID: W2115945685
FWCI: 14.1
Cites: 14
Cited by: 215
Related to: 10