Work

Under normoxia, 2-deoxy- d -glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation

Year: 2007

Type: article

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.mct-07-0310

Authors: Metin Kurtoglu, Ningguo Gao, Jie Shang, Johnathan C. Maher, Mark A. Lehrman, Medhi Wangpaichitr, Niramol Savaraj, Andrew N. Lane, Theodore J. Lampidis

Institutions: University of Miami, Sylvester Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Miami VA Healthcare System, University of Louisville

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: G2336309168, G4153319734, The N-Glycosylation Pathway And Signaling By Free Mannose-6-Phosphate, Anti-tumor Activity of Sugar Analogs via Blocking Glycolysis vs Glycosylation, G946336251

OpenAlex ID: W2116015672

FWCI: 2.226

Cites: 40

Cited by: 241

Related to: 10