Work

The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-κB, is dispensable for T cell development and/or T cell effector functions

Year: 2008

Type: article

Source: Molecular Immunology

DOI: 10.1016/j.molimm.2008.05.023

Authors: Jennifer A. Young, Amy M. Becker, Jennifer J. Medeiros, Virginia S. Shapiro, Andrew Wang, J. David Farrar, Timothy A. Quill, Rob Hooft van Huijsduijnen, Nicolai S.C. van Oers

Institutions: The University of Texas Southwestern Medical Center, University of Pennsylvania, Merck Serono S.A. (Switzerland)

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: G1277860013, PTPN4 Functions in Lymphocytes, G267413303, G2822269562, G656032834, T Cell Receptor Signaling by Phosphorylated Forms of TCR, Integrative Immunology Training Grant, G9000273223

OpenAlex ID: W2116206171

FWCI: 0.822

Cites: 78

Cited by: 33

Related to: 10