VX-770, a CFTR potentiator, may have a potential clinical benefit in a subgroup of people with cystic fibrosis
Year: 2011
Type: article
Abstract: Cystic fibrosis (CF) is caused by mutations in the gene encoding the CFTR (CF transmembrane conductance regulator) protein, an epithelial ion channel. Some mutations, of which the G551D mutation is the most common (occurring in approximately 5% of people with CF), permit the defective CFTR protein to reach the epithelial …
Source: Thorax
Author: S. Shah
Institution: Croydon University Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2116209774