Work

Androgen deficiency in older men: Indications, advantages, and pitfalls of testosterone replacement therapy

Year: 2012

Type: review

Abstract: The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established. While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual and marked by nonspecific symptoms. This makes diagnosis of true testosterone deficiency and prediction of response to testosterone replacement therapy (TRT) challenging. This article reviews androgen decline in men, focusing on those over age 40, and covers symptoms, indications, contraindications,diagnosis, treatments, and the risks and benefits of treatment [corrected].

Source: Cleveland Clinic Journal of Medicine

DOI: 10.3949/ccjm.79a.12010

Authors: John J. McGill, Daniel A. Shoskes, Edmund S. Sabanegh

Institutions: University Hospitals of Cleveland, University Hospitals Cleveland Medical Center, Cleveland Clinic, Glickman Urological Institute

Language: English

Topic: Hormonal and reproductive studies

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2116494987