Work

Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

Year: 2012

Type: article

Abstract: Hydrogen sulfide (H(2)S) is an important biological messenger but few biologically-compatible methods are available for its detection. Here we report two bright fluorescent probes that are selective for H(2)S over cysteine, glutathione and other reactive sulfur, nitrogen, and oxygen species. Both probes are demonstrated to detect H(2)S in live cells.

Source: Chemical Communications

DOI: 10.1039/c2cc30730h

Authors: Leticia A. Montoya, Michael D. Pluth

Institution: University of Oregon

Language: English

Topic: Sulfur Compounds in Biology

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Developing fluorescent probes for the endogenous gaseous transmitters NO and H2S