Work

The factors affecting effectiveness of treatment in phages therapy

Year: 2014
Type: review
Abstract: In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine, and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applications.
Language: English
Subfield: Virology
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W2116788484
FWCI: 2.139
Cites: 56
Cited by: 346
Related to: 10