Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
Year: 2009
Type: article
Abstract: In 2003, an international working group last reported on recommendations for diagnosis, response assessment, and treatment outcomes in acute myeloid leukemia (AML). Since that time, considerable progress has been made in elucidating the molecular pathogenesis of the disease that has resulted in the identification of new diagnostic and prognostic markers. Furthermore, therapies are now being developed that target disease-associated molecular defects. Recent developments prompted an international expert panel to provide updated evidence- and expert opinion-based recommendations for the diagnosis and management of AML, that contain both minimal requirements for general practice as well as standards for clinical trials. A new standardized reporting system for correlation of cytogenetic and molecular genetic data with clinical data is proposed.
Source: Blood
Authors: Hartmut Döhner, Elihu H. Estey, Sergio Amadori, Frederick R. Appelbaum, Thomas Büchner, Alan K. Burnett, Hervé Dombret, Pierre Fenaux, David Grimwade, Richard A. Larson, Francesco Lo-Coco, Tomoki Naoe, Dietger Niederwieser, Gert J. Ossenkoppele, Miguel A. Sanz, Jorge Sierra, Martin S. Tallman, Bob Löwenberg, Clara D. Bloomfield
Institutions: Universität Ulm, Seattle Cancer Care Alliance, University of Rome Tor Vergata, Fred Hutch Cancer Center, University of Münster, University of Wales, Assistance Publique – Hôpitaux de Paris, Hôpital Saint-Louis, Laboratoire d'hématologie, Hôpital Avicenne, University of Chicago, Fondazione Santa Lucia, Nagoya University Hospital, Leipzig University, Amsterdam UMC Location Vrije Universiteit Amsterdam, Hospital Universitari i Politècnic La Fe, Hospital de Sant Pau, Northwestern University, Erasmus MC, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2116858301