Measurement of Umbilical Arterial Blood Flow to the Sheep Placenta and Fetus in Utero: DISTRIBUTION TO COTYLEDONS AND THE INTERCOTYLEDONARY CHORION
Year: 1968
Type: article
Abstract: A method of estimating the magnitude and distribution of umbilical blood flow by means of radioactive microspheres in sheep fetuses in utero is described. Simultaneous measurements of total umbilical flow by this method and the steady-state diffusion technique showed agreement within ±11%. In 11 fetuses of 90 to 150 days gestational age, the distribution of umbilical flow to the intercotyledonary chorion was 6.2±0.8% of the total. This information has been used to estimate the effect of venous admixture of cotyledonary and noncotyledonary blood on the umbilical vein-uterine vein concentration difference of inert molecules with flow-limited transplacental clearance.
Source: Circulation Research
Institution: University of Colorado Denver
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2117246796