Work

An automated technique for measuring hippocampal volumes from MR imaging studies.

Year: 2001

Type: article

Abstract: We describe an automated volumetric measure of the hippocampus obtained with software called the Knowledge-Guided MRI Analysis Program (KGMAP). Postmortem MR images from 56 participants in the Nun Study were used to validate the measure. KGMAP-determined volumes strongly correlated with those obtained with manual tracings and neurofibrillary pathologic findings of Alzheimer disease in the hippocampus. KGMAP provides a rapid and accurate estimate of hippocampal volume that is suitable for use in clinical practice.

Source: PubMed Central

Authors: K M Gosche, J A Mortimer, C D Smith, W R Markesbery, D A Snowdon

Institution: University of South Florida

Language: English

Topic: Medical Image Segmentation Techniques

Subfield: Computer Vision and Pattern Recognition

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute on Aging

Awards: Independent and Dependent Life in the Elderly, ALZHEIMER'S DISEASE RESEARCH CENTER, EPIDEMIOLOGY OF AGING AND ALZHEIMER'S DISEASE