Effect of Low Intensity Exercise on Glucose Intolerance in The Depo Medroxyprogesterone Acetate (DMPA) Injected Rat
Year: 2006
Type: article
Abstract: Progesterone and derivate of progesterone-only contraceptive, such as injectable depo Medroxyprogesteron acetate (DMPA) increased diabetic risk. Glucose intolerance and hyperinsulinemia were found in women who had been four until twelve month injected 150 mg DMPA. Exercise reduces glucose intolerance in a lot of diabetic patients but the effect of exercise in women who had injected DMPA remains controversial. This study was to measure the effect of low intensity exercise on glucose intolerance injected DMPA rat. Glucose tolerance was tested on 32 female rats which divided into four groups group 1 was a group of control rats, group 2 had done low intensity exercise, group 3 was injected with 20 mg DMPA each week and the group 4 was DMPA injected rat which had done low intensity exercise for 12 weeks. It was found that plasma glucose rose significantly (p 0.05). In conclusion, low intensity exercise did not reduce glucose intolerance on DMPA injected female rat.
Source: Folia Medica Indonesiana
Authors: Bambang Purwanto, Lilik Herawati, Harjanto Jm
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $98
OpenAlex ID: W2117573992