Adherence to Antiretroviral Therapy and Its Association with Sexual Behavior in a National Sample of Women with Human Immunodeficiency Virus
Year: 2002
Type: article
Study design: Observational Study
Abstract: To delineate the relationship between adherence to human immunodeficiency virus (HIV) therapy and sexual behavior among HIV type 1-infected women in the United States, data were collected from October 1998 through March 1999 from 766 HIV-positive women on adherence to therapy, risk behavior, and disease markers. Adherence rates of >/=95% were reported by 66% of the patients. In multivariate analyses, patients with lower rates of adherence tended to be younger (odds ratio [OR], 1.69), to be active drug users (OR, 2.27), to have detectable virus load levels (OR, 2.00), and to have a lower quality of life (OR, 1.20). Among sexually active women, lower adherence rates were associated with an increased risk for inconsistent condom use (adjusted OR, 2.17). Although counseling regarding sexual behavior and adherence to treatment regimens are often addressed separately, our data highlight the importance of discussing these factors in relation to one another, particularly with regard to patients experiencing virologic failure.
Source: Clinical Infectious Diseases
DOI: 10.1086/338397
Authors: Tracey E. Wilson, Yolanda Barrón, Mardge Cohen, Jean Richardson, Ruth Greenblatt, Henry S. Sacks, Mary Young, for the Women's Interagency HIV Study
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: National Institutes of Health, Centers for Disease Control and Prevention, National Institute on Drug Abuse, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of Child Health and Human Development, National Institute of Dental and Craniofacial Research, National Center for Research Resources, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1025189317, G1290148215, G2462901743, G2600894462, WOMEN'S AIDS COHORT STUDY, The Connie Wofsy Women's HIV Study, G3414024915, Brooklyn Women's Interagency HIV Study (WIHS) V, WIHS Data Management and Analysis Center (WDMAC), G4538066223, Southern California Women's Interagency HIV Study Consortium, General Clinical Research Center, G498379488, Chicago WIHS Consortium V (CWC), G508464731, Washington Women's Interagency HIV/AIDS Study, G699655281, G769023845, Women's Interagency HIV Study (WIHS-V), General Clinical Research Center
OpenAlex ID: W2117612106