Year: 2014
Type: article
Abstract: Magnetic biosensors, based on nanomaterials and miniature electronics, have emerged as a powerful diagnostic platform. Benefiting from the inherently negligible magnetic background of biological objects, magnetic detection is highly selective even in complex biological media. The sensing thus requires minimal sample purification and yet achieves a high signal-to-background contrast. Moreover, magnetic sensors are also well-suited for miniaturization to match the size of biological targets, which enables sensitive detection of rare cells and small amounts of molecular markers. We herein summarize recent advances in magnetic sensing technologies, with an emphasis on clinical applications in point-of-care settings. Key components of sensors, including magnetic nanomaterials, labeling strategies and magnetometry, are reviewed.
Source: Lab on a Chip
DOI: 10.1039/c4lc00314d
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
Awards: G1016679917, G1098359285, G1151953971, Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas, Novel Clickdyes for Biomedical Sensing, G2066243351, G4540770348, A micro Hall chip for circulating microvesicle based cancer monitoring, G531578462, The MIT-Harvard Center of Cancer Nanotechnology Excelle*, G7521024345, G9000010793, G9000056315, G9000153364, G9000194433, Dana Farber/Harvard Cancer Consortium Career Development Program in Clinical Oncology, G947370982
OpenAlex ID: W2117649406