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Prospective motion correction for single‐voxel 1H MR spectroscopy

Year: 2010
Type: article
Abstract: Head motion during (1)H MR spectroscopy acquisitions may compromise the quality and reliability of in vivo metabolite measurements. Therefore, a three-plane image-based motion-tracking module was integrated into a single-voxel (1)H MR spectroscopy (point-resolved spectroscopy) sequence. A series of three orthogonal spiral navigator images was acquired immediately prior to the MR spectroscopy water suppression module in order to estimate head motion. By applying the appropriate rotations and translations, the MR spectroscopy voxel position can be updated such that it remains stationary with respect to the brain. Frequency and phase corrections were applied during postprocessing to reduce line width and restore coherent averaging. Spectra acquired during intentional head motion in 11 volunteers demonstrate reduced lipid contamination and increased spectral reproducibility when motion correction is applied.
DOI: 10.1002/mrm.22448
Authors: Brian Keating, Weiran Deng, J. Cooper Roddey, Nathan White, Anders Dale, V. Andrew Stenger, Thomas Ernst
Language: English
Field: Medicine
Open Access status: bronze
Funders: National Institutes of Health, U.S. Public Health Service, National Institute on Drug Abuse, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources
Awards: RGR-based motion tracking for real-time adaptive MR imaging and spectroscopy, G1244017850, Imaging Studies in Neurotoxicity and Neurodevelopment, Bioscience Research Infrastructure Development for Grant Enhancement and Success, G43489937, Spectral Spatial RF Pulses for Gradient Echo fMRI, G609369607, G7165415505, G876179694, G9000065621, G9000321635
OpenAlex ID: W2117935525
FWCI: 3.134
Cites: 15
Cited by: 50
Related to: 10