Year: 2014
Type: article
Study design: Observational Study
Abstract: We investigated changes in bone mineral density (BMD) and relevant factors of BMD in patients with type 1 diabetes (T1D). A total of 47 patients with T1D and 40 healthy controls participated in this study. The waist-to-hip ratio (WHR) and body mass index (BMI) were calculated after physical examination. The lumbar spine (L2-L4) BMD and left femoral neck BMD were examined. Blood samples were collected. The BMI, WHR, fasting C peptide (FCP), postprandial C peptide (2hCP), lumbar spine and left femoral neck BMD of the patients with T1D were significantly lower than those of healthy controls, while the fasting plasma glucose (FPG), postprandial plasma glucose (2hPG) and hemoglobin A1c (HbA1c) were higher (P <0.05). Duration of T1D and HbA1c were negatively correlated with lumbar spine and left femoral neck BMD. The FCP and 2hCP were positively correlated with lumbar spine and left femoral neck BMD.
Source: Archives of Biological Sciences
DOI: 10.2298/abs1403091d
Authors: Peng Duan, Ping Tu, Heping Wu, Xun Ding, Jiang Liu, Deng Bo
Institution: Third Hospital of Nanchang
Language: English
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2117984321