Work

A Mutant of Mycobacterium smegmatis Defective in Dipeptide Transport

Year: 1998

Type: article

Abstract: A mutant of Mycobacterium smegmatis unable to use the dipeptide carnosine (beta-alanyl-L-histidine) as a sole carbon or nitrogen source was isolated. Carnosinase activity and the ability to grow on beta-Ala and/or L-His were similar in the mutant and the wild type. However, the mutant showed significant impairment in the uptake of carnosine. This study is the first description of a peptide utilization mutant of a mycobacterium.

Source: Journal of Bacteriology

DOI: 10.1128/jb.180.24.6773-6775.1998

Authors: Achal Bhatt, Renee Green, Roswell Coles, Michael Condon, Nancy D. Connell

Institution: Rutgers New Jersey Medical School

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Award: NUTRIENT TRANSPORT MECHANISMS IN MYCOBACTERIA