Work

System Integration - A Major Step toward Lab on a Chip

Year: 2011

Type: article

Abstract: Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications.

Source: Journal of Biological Engineering

DOI: 10.1186/1754-1611-5-6

Authors: Mandy LY Sin, Jian Gao, Joseph C Liao, Pak Kin Wong

Institutions: University of Arizona, Shandong Polytechnic, Stanford Medicine, Stanford University, BIO5 Institute

Language: English

Topic: Microfluidic and Capillary Electrophoresis Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,890

Funders: National Science Foundation, National Institutes of Health, National Institute of Allergy and Infectious Diseases