Work

Regulatory T CELLS Specific for Minor Histocompatibility Antigens

Year: 2013

Type: article

Abstract: After hematopoietic cell transplantation (HCT), the risk of acute graft-vs.-host disease (GVHD) is increased in male recipients of female grafts. Disparities for the male-associated H-Y and other minor histocompatibility antigens (mHAs) have the capacity to sensitize alloreactive donor T cells and cause GVHD in HLA-matched recipients. We asked whether regulatory T cells (Treg) exist specific for human mHA.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2012.11.203

Authors: Anandaraman Veerapathran, Francisca Beato, Joseph Pidala, William Janssen, Xue-Zhong Yu, Claudio Anasetti

Institution: Moffitt Cancer Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650