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Enhancing T cell persistence of CAR-redirected T cells in solid tumors

Year: 2014
Type: article
Abstract: Meeting abstracts T cell persistence is likely to promote long-term anti-tumor effects after adoptive T cell transfer. We have recently shown that incorporation of the ICOS intracellular domain into chimeric antigen receptors (CARs) significantly increased Th17 cell persistence in vivo , compared
DOI: 10.1186/2051-1426-2-s3-p244
Authors: Sonia Guedan, Shannon E McGettigan, Avery D Posey, Jihyun Lee, Omkar Kawalekar, Prachi R Patel, Brian Keith, Carl June
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2118217504
FWCI: 0.144
Cites: 1
Cited by: 1
Related to: 10