Work

Butadiene sulfone as ‘volatile’, recyclable dipolar, aprotic solvent for conducting substitution and cycloaddition reactions

Year: 2015

Type: article

Abstract: Butadiene sulfone has been employed as a “volatile”, recyclable dipolar, aprotic solvent in the reaction of benzyl halide with metal azides to form benzyl azide (1) and the subsequent reaction of benzyl azide with p-toluenesulfonyl cyanide (3) to produce 1-benzyl-5-(p-toluenesulfonyl)tetrazole (2). Comparisons are made with the solvent DMSO and an analogous sulfolene solvent—piperylene sulfone. In addition, recycling protocols for butadiene sulfone and piperylene sulfone are also presented.

Source: Sustainable Chemical Processes

DOI: 10.1186/s40508-015-0040-7