Work

Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife.

Year: 2004
Type: article
Abstract: Nonsense-mediated mRNA decay (NMD) downmodulates mRNAs that have in-frame premature termination codons and prevents translation of potentially harmful truncated proteins from aberrant mRNAs. Two new approaches have identified physiological NMD substrates, and suggest that NMD functions as a multipurpose tool in the modulation of gene expression.
Language: English
Open Access status: gold
Estimated APC paid: $5,490
OpenAlex ID: W2118856460
FWCI: 3.717
Cites: 24
Cited by: 76
Related to: 10