Work

"In vitro" activities of antimycobacterial agents against Mycobacterium avium subsp. paratuberculosis linked to Crohn's Disease and Paratuberculosis

Year: 2006

Type: article

Abstract: Crohn's disease, a human disease similar to paratuberculosis in animals is the most painful and devastating disease that may involve infection withM. aviumsubsp.paratuberculosis(MAP), different genetic polymorphisms and an immune dysregulation syndrome. Treatment of Crohn's disease is most commonly based on 5-aminosalicylic acid (5-ASA) compounds, corticosteroids, and immunosuppressive agents. Recently, biological therapies using monoclonal antibodies against inflammatory cytokines have shown some positive results. However, all these therapies treat the symptoms not the cause of the disease.

Source: Annals of Clinical Microbiology and Antimicrobials

DOI: 10.1186/1476-0711-5-27

Authors: Stefania Zanetti, Paola Molicotti, Sara Cannas, Silvia Ortu, Niyaz Ahmed, Leonardo A Sechi

Institutions: University of Sassari, Centre for DNA Fingerprinting and Diagnostics

Language: English

Topic: Mycobacterium research and diagnosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,190