Work

In Vitro Activities of Terbinafine against Aspergillus Species in Comparison with Those of Itraconazole and Amphotericin B

Year: 2001

Type: article

Abstract: Compared with the in vitro activities of itraconazole (geometric mean MIC [GM], 0.56 microg/ml) and amphotericin B (GM, 0.66 microg/ml), the in vitro activity of terbinafine was inferior against Aspergillus fumigatus (GM, 19.03 microg/ml) (P < 0.05) and superior against A. flavus (GM, 0.10 microg/ml), A. terreus (GM, 0.16 microg/ml), and A. niger (GM, 0.19 microg/ml). Clinical correlation is required, as trailing endpoints are problematic.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.45.6.1882-1885.2001

Authors: Caroline B. Moore, Caroline M. Walls, David W. Denning

Institutions: Salford Royal Hospital, North Manchester General Hospital, University of Manchester

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2119511131

FWCI: 3.616

Cites: 16

Cited by: 56

Related to: 10