Year: 2007
Type: letter
Abstract: A recent PLoS Biology article [1] rejected the conclusions of two previous publications [2,3] that two categories of highly connected "hub" proteins-"date" and "party" hubs-have distinct properties in the Saccharomyces cerevisiae interactome network.Currently available protein-protein interaction datasets are vastly incomplete, even for yeast [4].Therefore, it is reasonable to rigorously re-scrutinize global properties of interactome networks as new datasets become available.Here we show that distinctions between date and party hubs [2], previously shown in a high-quality fi ltered yeast interactome (FYI) dataset [2,3], are in fact confi rmed in an updated literature-curated yeast interactome network.
Source: PLoS Biology
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $5,500
OpenAlex ID: W2119782490