Work

Expanding the Reaction Scope of DNA-Templated Synthesis

Year: 2002

Type: article

Abstract: Powerful reactions such as Wittig olefinations, nitro-aldol additions, dipolar cycloadditions, and Heck coupling reactions can be mediated by DNA templates. The yields of several DNA-templated reaction products are independent of the number of bases (n=0 or 10) separating the annealed reactive groups (as an example, the denaturing polyacrylamide gel electrophoresis of a DNA-templated Wittig reaction is shown).

Source: Angewandte Chemie International Edition

DOI: 10.1002/1521-3773(20020517)41:10<1796::aid-anie1796>3.0.co;2-z

Authors: Zev J. Gartner, Matthew W. Kanan, David R. Liu

Institution: Harvard University

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2120435341

FWCI: 5.561

Cites: 19

Cited by: 192

Related to: 10