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From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond

Year: 2010
Type: article
Abstract: The discovery of the Src oncogene was the first step on a long journey toward improved cancer chemotherapy. In this review, we explore Src and BCR-ABL, signal transduction, and recent advances in oncogene addiction and celebrate Hidesaboro Hanafusa and the many researchers who ushered in the age of target-directed therapy against tyrosine kinase oncoproteins.
DOI: 10.1177/1947601911407327
Institutions: Brigham and Women's Hospital, Harvard University, Broad Institute, Boston Children's Hospital, Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Manton Center for Orphan Disease Research
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: green
OpenAlex ID: W2120529083
FWCI: 0.601
Cites: 109
Cited by: 3
Related to: 10