Work

An explanation for the decrease in cell lysis in a rotating tube with increasing ultrasound intensity

Year: 1989

Type: article

Abstract: Previous observations indicate that for in vitro mammalian cells insonated in rotating test tube the amount of cell lysis initially increases to some maximum and then decreases with further increase in ultrasound exposure. The results of the present investigation support the postulate that the reduction in cell lysis with increase in ultrasound intensity is related to the development of an ultrasonically induced "cloud" of bubbles in the fluid between the transducer and test tube; these bubbles mitigate against acoustic transmission thus reducing cell lysis in the insonated test tube.

Source: Ultrasound in Medicine & Biology

DOI: 10.1016/0301-5629(89)90134-8

Authors: Morton W. Miller, Charles C. Church, Andrew A. Brayman, Michelle S. Malcuit, Robert W. Boyd

Institutions: University of Rochester Medicine, University of Rochester

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,650