Year: 2010
Type: dissertation
Abstract: Kidney transplantation is the preferred treatment of choice for almost all categories of patients\nwith end-stage-renal disease (ESRD) including those with hypertension, glomerulonephritis,\ndiabetes mellitus and genetic causes as polycystic renal disease. Transplanted patients will\nlive approximately 10-15 years longer than patients that remain on dialysis. In light of the\nincreased donor shortage and the increasing waiting time, the number of kidney transplants\nfrom living donors enormously increased during the last decade. Complete matching for\nmajor Human Leucocyte Antigen (HLA) molecules between donor and recipients is preferable,\nbut due to the high degree of polymorphism of HLA, only some recipients with a suitable\nliving-related sibling donor receive a fully HLA-identical donor kidney.
Author: Jeroen H. Gerrits
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Nierstichting
OpenAlex ID: W2121357165