Work

Identification of 16S rRNA Methylase-Producing Acinetobacter baumannii Clinical Strains in North America

Year: 2007

Type: article

Abstract: Five highly amikacin-resistant Acinetobacter baumannii isolates were collected at a medical center in Pennsylvania. The aminoglycoside resistance was due to the production of the 16S rRNA methylase ArmA. Two of the isolates coproduced OXA-23 beta-lactamase and were highly resistant to carbapenems as well. The isolates were genetically closely related by pulsed-field gel electrophoresis.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00560-07

Authors: Yohei Doi, Jennifer M. Adams, Kunikazu Yamane, David L. Paterson

Institutions: University of Pittsburgh Medical Center, National Institute of Infectious Diseases, Queensland Health, The University of Queensland, Royal Brisbane and Women's Hospital

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases