Work

Obesity and Headache: Part II – Potential Mechanism and Treatment Considerations

Year: 2014

Type: article

Abstract: Obesity and headache are both associated with a substantial personal and societal impact, and epidemiologic studies have consistently identified a positive association between obesity and headache in general, as well as obesity and migraine specifically (see part I). In the current manuscript, we will discuss the potential mechanisms for the migraine-obesity association, with a focus on the central and peripheral pathophysiological pathways which overlap between migraine and those modulating the drive to feed. We then discuss surgical, behavioral, and pharmacological treatment considerations for overweight and obese migraineurs as well as for those with idiopathic intracranial hypertension. We close by briefly discussing where future research may be headed in light of this data.

Source: Headache The Journal of Head and Face Pain

DOI: 10.1111/head.12297

Authors: Nu Cindy Chai, Dale S. Bond, Abhay Moghekar, Ann I. Scher, B. Lee Peterlin

Institutions: Johns Hopkins University, Brown University, Uniformed Services University of the Health Sciences

Language: English

Topic: Migraine and Headache Studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Neurological Disorders and Stroke